Rituxan® is a monoclonal antibody that targets CD20-positive B cells, which contribute to autoimmune and hematologic diseases. It is used in both rheumatology and oncology settings.
therapies we administer
Conditions Treated
- Rheumatoid Arthritis (RA)
- Vasculitis (e.g., Granulomatosis with Polyangiitis)
- Certain blood cancers (by oncology referral)
How It Works
Rituxan® binds to CD20, a protein on B cells, leading to their destruction. This reduces autoantibody production and immune system overactivity.
Infusion Schedule & Duration
- Induction: 2 infusions, 2 weeks apart
- Maintenance: Every 6 months
- Infusion Time: 3–5 hours for initial doses
- Pre-meds: Steroids, antihistamines, acetaminophen
What to Expect
- Extended monitoring during infusion
- Reduced frequency of treatment over time
- Possible repeat lab testing to track response
Potential Side Effects
- Infusion reactions
- Fever or chills
- Fatigue or low blood pressure
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Referrals & Insurance
Requires a referral from a licensed physician. Prior authorization may be necessary.